Kamagra is a highly effective oral medication used for the treatment of Erectile Dysfunction (ED) in men. It contains Sildenafil Citrate, a potent compound that increases blood flow to the penis, helping men achieve and maintain an erection during sexual stimulation. Kamagra belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which also includes other medications like Viagra, Cialis, and Levitra.

What is Kamagra?

Kamagra is a prescription-only medication manufactured by reputable pharmaceutical companies such as Ajanta Pharma Ltd. It is available in 50mg and 100mg dosages in tablet form. The active ingredient, Sildenafil Citrate, is well-documented for its ability to treat erectile dysfunction and pulmonary arterial hypertension (PAH).

How Kamagra Works

Kamagra enhances the body’s natural erectile response by supporting the NO-cGMP pathway:

1. Sexual stimulation triggers the release of nitric oxide (NO) in the corpus cavernosum of the penis.
2. NO activates guanylate cyclase, an enzyme that increases the levels of cyclic guanosine monophosphate (cGMP).
3. Increased cGMP relaxes smooth muscle tissue and allows blood to flow into the penis, resulting in an erection.
4. Sildenafil, the main ingredient in Kamagra, inhibits the PDE5 enzyme, which breaks down cGMP. By blocking PDE5, Kamagra helps maintain higher levels of cGMP for a longer duration.

Note: Kamagra only works in the presence of sexual arousal. It does not cause erections without stimulation.

Pharmacological Properties

• Formula: C₂₂H₃₀N₆O₄S
• Average Molecular Weight: 474.576
• Protein Binding: Approximately 96%
• Bioavailability: 41%
• Time to Peak Concentration: 30-120 minutes
• Half-life: 3 to 5 hours
• Excretion: 80% in feces, 13% in urine

Clinical Effectiveness

Clinical studies involving over 1,500 patients show that Kamagra significantly improves erectile function in men with ED. Double-blind, placebo-controlled trials using objective tools like RigiScan® confirm enhanced hardness and duration of erections when compared to placebo. Most men report optimal effects within 60 minutes of administration, with duration lasting up to 4 hours.

Dosage and Administration

Kamagra is intended for oral use and should be taken with a full glass of water.

Recommended Dosage:

• Initial Dose: 50 mg, taken 30-60 minutes before sexual activity
• Maximum Dose: 100 mg per day
• Minimum Dose: 25 mg for elderly patients or those with liver/kidney issues

Special Considerations:

• Take on an empty stomach or after a light meal
• Avoid high-fat meals before taking the tablet as it may delay absorption
• Do not exceed one dose per day

Side Effects of Kamagra

Most side effects of Kamagra are mild and temporary. However, serious reactions may occur in rare cases.

Common Side Effects:

• Headache
• Flushing (warmth or redness in the face)
• Dizziness
• Nasal congestion
• Indigestion
• Vision disturbances (blurred or tinted vision)

Less Common Side Effects:

• Chest pain
• Irregular heartbeat
• Priapism (erection lasting more than 4 hours)
• Allergic reactions (swelling, breathing issues)
• Nausea and dry mouth

Seek immediate medical attention if severe symptoms or allergic reactions occur.

Precautions and Warnings

Kamagra should not be used without consulting a doctor, especially if you have:

• Cardiovascular disease
• History of stroke or heart attack
• Retinitis pigmentosa
• Hypotension or uncontrolled hypertension
• Liver or kidney impairment
• Deformities of the penis or risk of priapism

Drug and Food Interactions

Kamagra may interact with several drugs:

Major Interactions:

• Nitrates (e.g., nitroglycerin)
• Tadalafil
• Ritonavir

Moderate Interactions:

• Metoprolol
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
• Alpha-blockers

Food Interaction:

Avoid grapefruit or grapefruit juice, which may increase Sildenafil levels and delay its onset. Limit alcohol consumption as it may reduce Kamagra’s effectiveness and increase side effects.

Storage Instructions

• Store Kamagra below 30°C
• Keep in a dry place away from direct sunlight
• Keep out of reach of children

Contraindications

Kamagra is not suitable for:

• Patients using organic nitrates
• Patients with severe cardiac conditions
• Women, children, or infants

Frequently Asked Questions (FAQs)

What is Kamagra used for?

Kamagra is used to treat erectile dysfunction and, in some cases, pulmonary arterial hypertension.

How long does Kamagra last?

Kamagra’s effects can last up to 4 hours, with peak effectiveness around 1–2 hours after intake.

Can I take Kamagra every day?

Yes, but no more than once per 24 hours, and only if prescribed by your doctor.

Is Kamagra safe for women?

Kamagra is not approved for use in women and should not be taken during pregnancy or breastfeeding.

Can Kamagra help me last longer?

Kamagra is designed to help achieve and maintain erections. It is not officially approved for premature ejaculation, though some users report longer performance.

What happens if I take Kamagra with alcohol?

Alcohol can reduce the effectiveness of Kamagra and increase side effects like dizziness and flushing.

Is Kamagra safe for older men?

Yes, but older adults may be more sensitive to side effects. A lower starting dose (25 mg) is usually recommended.

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